IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

Click here for Number of genes as deduced by RFLP analysis.

RFLP analysis suggests that a third gene of IGLC1 subgroup (corresponding to IGLC1, IGLC4 and IGLC5 IMGT gene names) is probably present in MAI and MBK strains [2].
RFLP analysis suggests that there are 6 to 7 IGLC2 subgroup genes (corresponding to IGLC2 and IGLC3 IMGT gene names) in MAI, MBK and PWK [2].

IMGT gene name	IMGT allele name	Fct		Chromosomal localization		T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences								IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct		Chromosomal localization		T	Pr	Positions in the locus	Strain	Clone names	Exons		Accession numbers	Positions in the sequence (C-REGION)		Secondary accession numbers	Strain	Clone names	Accession numbers	Positions in the sequence (C-REGION)
	IGLC1		(1)
	IGLC2	IGLC2*01		F						SPE	Clambda2SPE	MAP		M16554	[1]
	IGLC2	IGLC2*02		F						B6.lambdaSEG	Clambda2SEG	MAP		AF357973	[2]
	IGLC3		(1)
	IGLC4	IGLC4*01		P	(2)					SPE	Clambda4S (Clambda4SPE)	MAP		M16628	[1]
	IGLC4	IGLC4*02		P	(2)					B6.lambdaSEG	Clambda4SEG1	MAP		AF357972	[2]
	IGLC5	IGLC5*01		F	(3)					B6.lambdaSEG	Clambda4SEG2	MAP		AF357974	[2]

MAP: Mapped reference sequences.

IMGT notes:

(1) The cluster IGLV1-IGLJ3-IGLC3-IGLJ1-IGLC1 is deleted in B6.lambdaSEG and probably also in the lost strain SPE [2].
(2) Several DELETIONS leading to frameshifts and STOP-CODONS.
(3) IGLC5 is preceded by IGLJ5 which is an ORF.

IMGT references:

[1] Mami F. and Kindt T.J., J. Immunol., 138, 3980-3985 (1987). PMID:2820875
[2] Amrani Y.M. et al., Immunogenetics, 54, 106-119 (2002). PMID:12037603

See also (IMGT Scientific chart):

Created:: 03/11/1999
Last updated:: 22/09/2023
Authors:: Dominique Scaviner, Delphine Guiraudou

IMGT Repertoire (IG and TR)

Gene table: western wild mouse (Mus spretus) IGLC