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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct Haplotypes T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGKC1 IGKC1*01 F K1 b4 K01360 [1] 4714-5024 X00231 [3]
IGKC1*02 F K1 b4var K01362 [2] 41-351
IGKC1*03 F K1 b5 K01363 [5] 4375-4688
IGKC1*04 F K1 b9 X00674 [6] 264-583
IGKC1*05 ORF K1 b9 mutant Basilea X03050 [8] (1) 296-615
IGKC1*06 F K1 b6 M37809 [10] 3700-4013
IGKC1*07 F K1 b95 M22542 [12] 993-1306
IGKC1*08 F K1 b6w2 Z48308 [13] 194-507
IGKC1*09 (F) K1 b9 pkb9-17D9 K01359 [14] #c 367-687
IGKC2 IGKC2*01 F K2 b4 X00232 [3] 2276-2592 V00885 [4]
K2 b9 X05801 [9]
IGKC2*02 F K2 b6 X05800 [9] 295-611
IGKC2*03 F K2 b95 K2bas2 (95) X56061 [11] (2) 504-820 M22543 [12]
IGKC2*04 (F) K2 b9 mutant Basilea pkbas-3C8 K01280 [7] #c 371-687

#c: rearranged cDNA sequence.

IMGT notes:
  1. (1) ORF because of non canonical ACCEPTOR-SPLICE sequence: naann instead of nagnn.
  2. (2) This allele was identified in the subspecies sp.algirus.
IMGT references:
  1. [1] Emorine L. et al., Proc. Natl. Acad. Sci. U.S.A., 80, 5709-5713 (1983). PMID:6412231
  2. [2] Heidmann O. and Rougeon F., Cell, 34, 767-777 (1983). PMID:6313207
  3. [3] Emorine L. and Max E.E., Nucleic Acids Res., 11, 8877-8890 (1983). PMID:6324107
  4. [4] Heidmann O. and Rougeon F., EMBO J., 2, 437-441 (1983). PMID:11894960
  5. [5] Emorine L. et al., Proc. Natl. Acad. Sci. U.S.A., 81, 1789-1793 (1984). PMID:6424123
  6. [6] Akimenko M.A. et al., Nucleic Acids Res., 12, 4691-4701(1984). PMID:6330679
  7. [7] Bernstein K.E. et al., J. Exp. Med., 159, 635-640 (1984). PMID:6420504
  8. [8] Lamoyi E. and Mage R.G., J. Exp. Med., 162, 1149-1160 (1985). PMID:3930650
  9. [9] Mariame B. et al., Nucleic Acids Res., 15, 6171-6179 (1987). PMID:3114714
  10. [10] Dreher K.L. et al., J.Immunol., 145, 325-330 (1990). PMID:2113556
  11. [11] Ayadi H. et al., Res.Immunol., 142, 191-197 (1991). PMID:1910198
  12. [12] Ayadi H. et al., Immunogenetics, 34, 201-207 (1991). PMID:1909995
  13. [13] van der Loo W. et al., Immunogenetics, 42, 333-341 (1995). PMID:7590966
  14. [14] McCartney-Francis N. et al., Proc. Natl. Acad. Sci. U.S.A., 81, 1794-1798 (1984). PMID:6424124
Created:
29/05/1997
Last updated:
22/09/2023
Authors:
Manuel Ruiz, Fatena Bellahcene