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Homo sapiens LILR and KIR genes of the Leucocyte Receptor Complex (LRC)

Homo sapiens LILR and KIR genes of the Leucocyte Receptor Complex (LRC) on chromosome 19 at 19q13.42

Cells Gene name NC positions Orientation Aliases Funct HGNC UniProt Gene ID mRNA and protein sequences MIM IMGT/3Dstructure-DB
Monocytes, Macrophages,
Dentritic cells, B lymphocytes
LILRB3 NC_000019.10 (54216278..54223087, complement) REV CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIRB F 6607 Q6PI73 11025 NM_001081450.2 - NP_001074919.2 604820
LILRA6 NC_000019.10 (54236592..54242768, complement) REV CD85b, ILT-8, ILT5, ILT8, LILRB3, LILRB6 F 15495 Q6PI73 79168 NM_024318.3 - NP_077294.3
LILRB5 NC_000019.10 (54250405..54257308, complement) REV CD85C, LIR-8, LIR8 F 6609 O75023 10990 NM_001081442.2 - NP_001074911.1 604814
LILRB2 NC_000019.10 (54273812..54281178, complement) REV CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10 F 6606 Q8N423 10288 NM_001080978.3 - NP_001074447.2 604815 2dyp, 2gw5, 4lla
LILRA3 REV CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4 F 6604 Q8N6C8 11026 NM_001172654.2 - NP_001166125.1 604818 3q2c
LILRA5 NC_000019.10 (54307070..54313139, complement) REV CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9 F 16309 A6NI73 353514 NM_021250.3 - NP_067073.1 606047 2d3v
LILRA4 NC_000019.10 (54333185..54339169, complement) REV CD85g, ILT7 F 15503 P59901 23547 NM_012276.4 - NP_036408.4 607517
LAIR1 NC_000019.10 (54353624..54370556, complement) REV CD305 F 6477 Q6GTX8 3903 XM_005277111 - XP_005277168 602992 3kgr, 3rp1
LAIR2 NC_000019.10 (54502797..54510690) FWD CD306 F 6478 Q6ISS4 3904 NM_002288 - NP_002279 602993
LILRA2 NC_000019.10 (54572997..54587560) FWD CD85H, ILT1, LIR-7, LIR7 F 6603 Q8N149 11027 NM_001130917.2 - NP_001124389.2 604812 2otp
LILRA1 NC_000019.10 (54593576..54602724) FWD CD85I, LIR-6, LIR6 F 6602 O75019 11024 NM_001278318.1 - NP_001265247.1 604810
LILRB1 NC_000019.10 (54616930..54638167) FWD CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7 F 6605 Q8NHL6 10859 NM_001081637.2 - NP_001075106.2 604811 1g0x, 1p7q, 1ufu, 1ugn, 1vdg, 3d2u, 4ll9, 4no0
LILRB4 NC_000019.10 (54643835..54670359) FWD CD85K, ILT-3, ILT3, LIR-5, LIR5 F 6608 Q8NHJ6 11006 NM_001278426.3 - NP_001265355.2 604821 1g0x, 1p7q, 1ufu, 1ugn, 1vdg, 3d2u, 4ll9, 4no0
LILRP1 NC_000019.10 (54696327..54698529) FWD ILT9, CD85l, LILRA6P P 15496 79167
LILRP2 NC_000019.10 (54707916..54713452) FWD CD85m; ILT10; LILRA5 P 15497 79166
NK cells, T cell subsets KIR3DX1 NC_000019.10 (54532692..54545768) FWD FLJ00060, LENG12 P 25043 Q9H7L2 90011 NR_026716
KIR3DL3 NC_000019.10 (54724447..54736536) FWD CD158Z, KIR3DL7, KIR44, KIRC1 F 16312 Q8N743 115653 NM_153443.4 - NP_056952.2 610095
KIR2DL3 NC_000019.10 (54738509..54753052) FWD CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIR2DS5,
KIRCL23, NKAT, NKAT2, NKAT2A, NKAT2B, p58
F 6331 P43628 3804 NM_015868.2 - NP_001017388.1 604938 1b6u
KIR2DL2 CD158B1, CD158b, NKAT-6, NKAT6, p58.2 F 6330 P43627 3803 NM_014219.2 - NP_055034.2 604937 1efx, 2dl2, 2dli
KIR2DP1 NC_000019.10 (54756012..54760768) FWD KIRY; KIRZ; KIR15; KIR2DL6 P 16344 554300
KIR2DL1 NC_000019.10 (54769805..54784326) FWD CD158A, KIR-K64, KIR221, NKAT, NKAT-1, NKAT1, p58.1 F 6329 P43626 3802 NM_014218.2 - NP_055033.2 604936 1im9, 1nkr
KIR3DP1 NC_000019.10 (54786362..54790418) FWD CD158c, KIR2DS6, KIR3DS2P, KIR48, KIRX P 16343 A8MWS1 548594 610604
KIR2DL4 NC_000019.10 (54803612..54814517) FWD CD158D, G9P, KIR-103AS, KIR103, KIR103AS F 6332 Q99706 3805 NM_001080770.1 - NP_001074239.1 604945
KIR3DL1 NC_000019.10 (54816438..54830778) FWD CD158E1, KIR/S1, NKAT-3, NKAT3, NKB1, NKB1B, KIR3DL1 F 6338 P43629 3811 NM_013289.2 - NP_037421.2 604946 3vh8, 3wuw
KIR3DS1 CD158E2, KIR-123FM, KIR-G1, NKAT-10, NKAT10 F 6340 Q14943 3813 NM_001083539.2 - NP_001077008.1
KIR2DL5A CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3 F 16345 Q8N109 57292 NM_020535.3 - NP_065396.1 605305
KIR2DL5B KIR2DL5, KIR2DL5.2, KIR2DLX F 16346 Q8NHK3 553128 NM_001018081.1 - NP_001018091.1 61572
KIR2DS3 NKAT7 F 6335 Q14952 3811 NM_012313.1 - NP_036445.1 604954
KIR2DS1 CD158H, CD158a, p50.1 F 6333 Q14954 3806 NM_014512.1 - NP_055327.1 604952
KIR2DS4 NC_000019.10 (54832676..54848569) FWD CD158I, KIR1D, KIR2DS1, KIR412, KKA3, NKAT-8, NKAT8 F 6336 P43632 3809 NM_001281971.1 - NP_001268900.1 604955 3h8n
KIR2DS5 CD158G, NKAT9 F 6337 Q14953 3810 NM_014513.2 - NP_055328.2 604956
KIR2DS2 183ActI, CD158J, CD158b, NKAT-5, NKAT5, cl-49 F 6334 P43631 100132285 NM_001291695.1 - NP_001278624.1 604953 1m4k, 4n8v
KIR3DL2 NC_000019.10 (54850443..54867215) FWD CD158K, NKAT-4, NKAT4, NKAT4B, p140 F 6339 P43630 3812 NM_001242867.1 - NP_001229796.1 604947

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Representation of the Homo sapiens LILR and KIR gene cluster on chromosome 19 at 19q13.42

Arrows show genes with a reverse (REV) orientation on the chromosome (IMGT Index > Genomic orientation)

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Created:
04/02/2015
Editor:
Amélie Houles
Contact:
Marie-Paule Lefranc