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Homo sapiens tumor necrosis factor (TNF) superfamily genes

Homo sapiens TNF superfamily genes and chromosomal localizations

Tumor necrosis factor (TNF) superfamily genes are according to the increasing number in the TNFSF.

Gene name Chromosomal localization NC positions Orientation Gene definition and aliases Funct HGNC UniProt Gene ID mRNA and protein sequences OMIM IMGT/3Dstructure-DB
TNF 6p21.3 NC_000006.12 (31575567..31578336) FWD tumor necrosis factor (TNF) superfamily member 2, TNFSF2, TNF-alpha, TNFA F TNF P01375 7124 NM_000594.3 - NP_000585.2 191160 3wd5, 4g3y, 3alq, 3it8, 1az5
LTA 6p21.3 NC_000006.12 (31560550..31574324) FWD lymphotoxin alpha, tumor necrosis factor (TNF) superfamily member 1, TNFSF1, LT F LTA P01374 4049 NM_001159740.2 - NP_001153212.1 153440 4mxv, 4mxw
LTB 6p21.3 NC_000006.12 (31580558..31582425, complement) REV lymphotoxin beta, tumor necrosis factor (TNF) superfamily member 3, TNFSF3, p33 F LTB Q06643 4050 NM_002341.1 - NP_002332.1 600978
CD40LG Xq26 NC_000023.11 (136648177..136660390) FWD CD40 ligand, CD40L, tumor necrosis factor ligand superfamily member 5, TNFSF5, tumor necrosis factor related activation protein, TRAP, CD154 F CD40LG P29965 959 NM_000074.2 - NP_000065.1 300386 1i9r, 1aly, 3qd6, 3lkj
CD70 19p13 NC_000019.10 (6585839..6591152, complement) REV tumor necrosis factor (TNF) superfamily member 7, TNFSF7, CD27LG, CD27L F CD70 P32970 970 NM_001252.4 - NP_001243.1 602840
EDA Xq12-q13.1 NC_000023.11 (69616067..70039472) FWD ectodysplasin A, "ectodermal dysplasia 1, anhidrotic" , ED1, EDA2, oligodontia 1, ODT1 F EDA Q92838 1896 NM_001399.4 - NP_001390.1 300451 1rj7, 1rj8
FASLG 1q23 NC_000001.11 (172659008..172666873) FWD Fas ligand, FasL, tumor necrosis factor (TNF) superfamily, member 6, TNFSF6, CD95-L, CD178 F FASLG P48023 356 NM_000639.2 - NP_000630.1 134638
TNFSF4 1q25 NC_000001.11 (173183731..173208072, complement) REV tumor necrosis factor (TNF) superfamily member 4, OX40 ligand, OX-40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, gp34, CD252 F TNFSF4 P23510 7292 NM_003326.4 - NP_003317.1 603594 2hev
TNFSF8 9q33 NC_000009.12 (114893343..114930595, complement) REV tumor necrosis factor (TNF) superfamily member 8, CD30LG, CD153 F TNFSF8 P32971 944 NM_001244.3 - NP_001235.1 603875
TNFSF9 19p13.3 NC_000019.10 (6528562..6535928) FWD tumor necrosis factor (TNF) superfamily, member 9, 4-1BB-L F TNFSF9 P41273 8744 NM_003811.3 - NP_003802.1 606182 2x29
TNFSF10 3q26 NC_000003.12 (172505508..172523507, complement) REV tumor necrosis factor (TNF) superfamily, member 10,TRAIL, CD253 F TNFSF10 P50591 8743 NM_003810.3 - NP_003801.1 603598 1d2q
TNFSF11 13q14 NC_000013.11 (42562736..42608013) FWD tumor necrosis factor (TNF) superfamily member 11, RANKL, TRANCE, osteoclast differentiation factor, ODF, OPGL, CD254 F TNFSF11 O14788 8600 NM_003701.3 - NP_003692.1 602642 1jtz
TNFSF12 17p13.1 NC_000017.11 (7549058..7557890) FWD tumor necrosis factor (TNF) superfamily member 12, TWEAK, APO3L, DR3LG F TNFSF12 O43508 8742 NM_003809.2 -NP_003800.1 602695 4ht1
TNFSF13 17p13.1 NC_000017.11 (7558292..7561608) FWD tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256 F TNFSF13 O75888 8741 NM_003808.3 -NP_003799.1 604472 1xu1, 1xu2, 1xut
TNFSF13B 13q32-q34 NC_000013.11 (108269420..108308484) FWD tumor necrosis factor (TNF) superfamily member 13B, BAFF, THANK, TALL1, TALL-1, BLYS, BLyS, B cell activating factor, B lymphocyte activator, CD257 F TNFSF13B Q9Y275 10673 NM_006573.4 - NP_006564.1 603969 4v46, 1kd7, 1oqe
TNFSF14 19p13.3 NC_000019.10 (6658135..6670588, complement) REV tumor necrosis factor (TNF) superfamily member 14, LIGHT, HVEM-L, CD258 F TNFSF14 O43557 8740 NM_003807.3 - NP_003798.2 604520 4en0, 4rsu
TNFSF15 9q32 NC_000009.12 (114784635..114806128, complement) REV tumor necrosis factor (TNF) superfamily member 15, TNF ligand-related molecule 1, TL1, TL1A, vascular endothelial cell growth inhibitor, VEGI, vascular endothelial growth inhibitor-192A, VEGI192A F TNFSF15 O95150 9966 NM_005118.3 - NP_005109.2 604052 2re9, 3mi8
TNFSF18 1q23 NC_000001.11 (173041220..173050963, complement) REV tumor necrosis factor (TNF) superfamily member 18 F TNFSF18 Q9UNG2 8995 NM_005092.3 - NP_005083.2 603898 3b93

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Representation of the Homo sapiens tumor necrosis factor (TNF) superfamily genes on chromosomes

Arrows show genes with a reverse (REV) orientation on the chromosome (IMGT Index > Genomic orientation)


Created:
30/11/2015
Authors:
Mélanie Arrivet, Souphatta Sasorith and Marie-Paule Lefranc
Contact:
Marie-Paule Lefranc