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Correspondence between C numberings

Correspondence between the IMGT unique numbering for C-DOMAIN, the IMGT exon numbering and the Kabat numberings: Human IGLC

The IMGT unique numbering for C-DOMAIN is used in the Protein displays.

Amino acids resulting from the splicing are shown between parentheses.

Colors of amino acids are according to IMGT Color menu for sequence alignments.

Strands, turns and loops for C-DOMAIN (1) IMGT unique numbering for C-DOMAIN C-REGION
IGLC amino acid translation X51755 [1] (2) IMGT exon numbering Kabat numbering [2]
1-106
1.8 - - -
1.7 - - -
1.6 - - -
1.5 (G) 1 107A
1.4 Q 2 108
1.3 P 3 109
1.2 K 4 110
1.1 A 5 111
A-STRAND 1 N 6 112
2 P 7 113
3 T 8 114
4 V 9 115
5 T 10 116
6 L 11 117
7 F 12 118
8 P 13 119
9 P 14 120
10 S 15 121
11 S 16 122
12 E 17 123
13 E 18 124
14 L 19 125
15 Q 20 126
AB-TURN 15.1 - - -
15.2 - - -
15.3 - - -
B-STRAND 16 A 21 127
17 N 22 128
18 K 23 129
19 A 24 130
20 T 25 131
21 L 26 132
22 V 27 133
23 C 28 134
24 L 29 135
25 I 30 136
26 S 31 137
BC-LOOP 27 D 32 138
28 F 33 139
29 Y 34 140
30 P 35 141
31 - - -
34 - - -
35 G 36 142
36 A 37 143
37 V 38 144
38 T 39 145
C-STRAND 39 V 40 146
40 A 41 147
41 W 42 148
42 K 43 149
43 A 44 150
44 D 45 151
45 G 46 152
CD-STRAND 45.1 S 47 153
45.2 P 48 154
45.3 V 49 155
45.4 K 50 156
45.5 A 51 157
45.6 - - -
45.7 - - -
D-STRAND 77 G 52 158
78 V 53 159
79 E 54 160
80 T 55 161
81 T 56 162
82 K 57 163
83 P 58 164
84 S 59 165
DE-TURN 84.1 K 60 166
84.2 Q 61 167
84.3 S 62 168
84.4 N 63 170
84.5 - - -
84.6 - - -
84.7 - - -
85.7 - - -
85.6 - - -
85.5 - - -
85.4 N 64 171
85.3 K 65 172
85.2 Y 66 173
85.1 A 67 174
E-STRAND 85 A 68 175
86 S 69 176
87 S 70 177
88 Y 71 178
89 L 72 179
90 S 73 180
91 L 74 181
92 T 75 182
93 P 76 183
94 E 77 184
95 Q 78 185
96 W 79 186
EF-TURN 96.1 - - -
96.2 - - -
F-STRAND 97 K 80 187
98 S 81 188
99 H 82 189
100 R 83 190
101 S 84 191
102 Y 85 192
103 S 86 193
104 C 87 194
FG-LOOP 105 Q 88 195
106 V 89 196
107 T 90 197
108 H 91 198
109 E 92 199
110 - - -
111 - - -
112 - - -
113 - - -
114 G 93 200
115 S 94 203
116 T 95 204
117 V 96 205
G-STRAND 118 E 97 206
119 K 98 207
120 T 99 208
121 V 100 209
122 A 101 210
123 P 102 211
124 T 103 212
125 E 104 213
126 C 105 214
127 S 106 215
128 - - 216
IMGT notes:
(1) IMGT labels (concepts of description) are written in capital letters.
(2) X51755 corresponds to the IGLC1*02 allele (Alignment of alleles: Human IGLC1) and to the Mcg+ Ke+ Oz- serological isotype (Isotypes: Human (Homo sapiens) IGLC).
References:
[1] Vasicek, T.J. and Leder, P., J. Exp. Med., 172, 609-620 (1990). PMID: 2115572
[2] Kabat, E.A. et al., Sequences of proteins of immunological interest. 5th Edition - US Department of Health and Human Services, NIH publication n° 91-3242, p 647 (1991).