Citing IMGT dynamic tools: Sanou G., Zeitoun G. et al. IMGT® at scale: FAIR, Dynamic and Automated Tools for Immune Locus Analysis, Nucleic Acids Research. 2025;,gkaf1024. doi: 10.1093/nar/gkaf1024 (Free Article) PMID: 41091930.
Program version: v. 

Add information about removed genes/alleles.
May 15th, 2025.

Add the possibility to obtain a gene table per strain (for mouse now and for other species later) and allotypes/isotypes for human.
September 25th, 2024.

Bibliographical references in alphabetic order, small design changes and addition of "NL" for non-localized gene.
June 14th, 2024.

Addition of 'Score for IMGT allele confirmation' as well as NCBI TPA accession numbers.
September 20th, 2023.

Implementation of the dynamic gene table.

Gene table legend:

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene, when the data have been confirmed by several studies.

Functionality is shown in parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

IMGT allele confirmation: A scoring system is employed to indicate the number of IMGT/LIGM-DB reference sequences and other sequences from the literature in which an IG or TR gene allele has been identified and annotated.

Removed genes/alleles
If a gene/allele existence or name has to be changed, the old name or gene/allele would be deleted and its name won't be reused. They are kept in the gene table for historical reasons.
A single star ()
indicates that an IG or TR gene allele is annotated in the reference sequence only.
Two stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in one sequence from the literature.
Three stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in at least two sequences from the literature.
In the Excel file, the stars are represented by the plus symbol (+).

Click on:
  • IMGT gene name to get the corresponding IMGT/GENE-DB entry (link).
  • IMGT allele name to see the corresponding Alignments of alleles (link).
  • Accession number to get the corresponding IMGT/LIGM-DB entry (link).
  • MAP: mapped sequences. Click to access GENE-DB «LOCALIZATION IN GENOME ASSEMBLIES» (link).
  • [number] to access the corresponding IMGT reference (popover).
  • (number) to see the corresponding IMGT note (popover).
Options:
  • You can show/hide columns (), download data () or put the table in fullscreen () using buttons.
See also (IMGT Scientific chart):
Select a species and a IMGT group to get the gene table:
Only IMGT available species/group are shown in the drop-down list.
The gene table can take several seconds to appear, please be patient.

For a given gene name, each horizontal line corresponds to a different allele. For more information, see Alignments of alleles and Tables of alleles (IMGT Repertoire).

IGLV gene names are designated by a number for the subgroup [1,23,24], followed by a dash and a number for the localization from 3' to 5' in the locus.
In the IGLV gene name column, the IGLV genes are listed, for each subgroup, according to their position from 3' to 5' in the locus.
Pseudogenes which could not be assigned to subgroups with functional genes are designated by a roman number between parentheses, corresponding to the clans [26], followed by a dash and a number for the localization from 3' to 5' in the locus.

The 11 human (Homo sapiens) IGLV subgroups belong to five clans (Figure IGLV clans). Two additional clans only contain pseudogenes. Clans comprise, respectively:

Gene table of human (Homo sapiens) IGLV (clans) IMGT group:
IMGT sub­groupIMGT gene nameIMGT allele nameScore for
IMGT allele
confirmation		FctChromosomosal
localization		R T PrIMGT/LIGM-DB reference sequencesIMGT/LIGM-DB sequences from the literature
Clone namesAccession
numbers		Positions
in the sequence
(L-V-GENE-UNIT)
or V-REGION (*)		Secondary
accession
numbers		Clone namesAccession
numbers		Positions
in the sequence
(L-V-GENE-UNIT)
or V-REGION (*)
IGLV(I)IGLV(I)-11-1 IGLV(I)-11-1*01 P (1) 22q11.2 174779_ABC12_000046886900_P4 AC279423 [14] MAP <22443-22620 * BK075720✤ [12] 771025-771202 *
BK075721✤ [12] 770932-771109 *
IMGT000225 [5,10] ° <758433-758610 *
IMGT000280 [13] ° 774422-774599 *
IMGT000293 [3,8] 771057-771234 *
IMGT000318 [11] 765229-765406 *
IMGT000319 [7] 780412-780589 *
IMGT000329 [7] 786011-786188 *
IGLV(I)IGLV(I)-20 IGLV(I)-20*01 (43) P 22q11.2 V1-6P D87007 [9] MAP 15573-15858 * AC279210 [15] 16594-16879 *
BK075720✤ [12] 711781-712066 *
BK075721✤ [12] 711703-711988 *
IMGT000225 [5,10] ° 699083-699368 *
IMGT000280 [13] ° 715162-715447 *
IMGT000293 [3,8] 711796-712081 *
IMGT000318 [11] 706022-706307 *
IMGT000319 [7] 721164-721449 *
IMGT000329 [7] 726794-727079 *
IGLV(I)IGLV(I)-20 IGLV(I)-20*02 (43) P (2) 22q11.2 AC279208 [15] MAP 19943-20228 * AC279219 [15] 19943-20228 *
IGLV(I)IGLV(I)-34-1 IGLV(I)-34-1*01 P (3) 22q11.2 IMGT000225 [5,10] ° MAP 548704-549194 BK075720✤ [12] 561309-561799
BK075721✤ [12] 561330-561820
IMGT000280 [13] ° 564672-565162
IMGT000293 [3,8] 561294-561784
IMGT000318 [11] 555563-556053
IMGT000319 [7] 570718-571208
IMGT000329 [7] 576470-576960
IGLV(I)IGLV(I)-34-2 IGLV(I)-34-2*01 P (4) 22q11.2 IMGT000225 [5,10] ° MAP 449586-449852 * BK075720✤ [12] 462201-462467 *
BK075721✤ [12] 462209-462475 *
IMGT000293 [3,8] 462211-462477 *
IMGT000318 [11] 456435-456701 *
IMGT000319 [7] 471571-471837 *
IMGT000329 [7] 477322-477588 *
IGLV(I)IGLV(I)-34-2 IGLV(I)-34-2*02 P (5) 22q11.2 IMGT000280 [13] ° MAP 465536-465802 *
IGLV(I)IGLV(I)-38 IGLV(I)-38*01 (44) P 22q11.2 V1-12P D87009 [9] MAP 7092-7382 *
IGLV(I)IGLV(I)-38 IGLV(I)-38*02 P (1) 22q11.2 ABC10_2_1_000043666500_D13 OL352722 [14] MAP <26564-26854 * BK075720✤ [12] 422360-422855
BK075721✤ [12] 422367-422862
IMGT000225 [5,10] ° 409746-410241
IMGT000280 [13] ° 425857-426147 *
IMGT000319 [7] 431770-432265
IMGT000329 [7] 437521-438016
IGLV(I)IGLV(I)-38 IGLV(I)-38*03 P (6) 22q11.2 IMGT000293 [3,8] MAP 422374-422869 IMGT000318 [11] 416597-417092
IGLV(I)IGLV(I)-42 IGLV(I)-42*01 (44) P 22q11.2
RTPr
--
 VlambdaA X14613 [1,2] 336-624 * V1-15P D86999 [9] 36674-36964 *
IGLV(I)IGLV(I)-42 IGLV(I)-42*02 P (7) 22q11.2 IMGT000225 [5,10] ° MAP 380957-381451 BK075720✤ [12] 393576-394070
BK075721✤ [12] 393572-394066
IMGT000280 [13] ° 387777-388271
IMGT000293 [3,8] 393585-394079
IMGT000318 [11] 387801-388295
IMGT000319 [7] 393894-394388
IMGT000329 [7] 399643-400137
IGLV(I)IGLV(I)-45-1 IGLV(I)-45-1*01 P (8) 22q11.2 IMGT000225 [5,10] ° MAP 354760-355050 * BK075720✤ [12] 367402-367692 *
BK075721✤ [12] 367398-367688 *
IMGT000318 [11] 361635-361925 *
IGLV(I)IGLV(I)-45-1 IGLV(I)-45-1*02 P (9) 22q11.2 IMGT000280 [13] ° MAP 361571-361908 IMGT000293 [3,8] 367385-367722
IMGT000319 [7] 367703-367993 *
IMGT000329 [7] 373460-373750 *
IGLV(I)IGLV(I)-48-1 IGLV(I)-48-1*01 P (10) 22q11.2 IMGT000225 [5,10] ° MAP <331765-332060 * IMGT000293 [3,8] 344416-344711 *
IMGT000318 [11] 338632-338927 *
IGLV(I)IGLV(I)-48-1 IGLV(I)-48-1*02 P (10) 22q11.2 IMGT000280 [13] ° MAP <338582-338883 * BK075720✤ [12] 338385-338686 *
BK075721✤ [12] 338381-338682 *
IMGT000319 [7] 344703-345004 *
IMGT000329 [7] 344445-344746 *
IGLV(I)IGLV(I)-56 IGLV(I)-56*01 (45) P (11) 22q11.2 V1-21P D86996 [9] MAP 12276-12571 * AC279220 [15] 3138-3433 *
BK075720✤ [12] 189320-189615 *
BK075721✤ [12] 189324-189619 *
IMGT000225 [5,10] ° 182649-182944 *
IMGT000280 [13] ° 189293-189588 *
IMGT000293 [3,8] 195340-195635 *
IMGT000318 [11] 189548-189843 *
IMGT000319 [7] 195418-195713 *
IMGT000329 [7] 195382-195677 *
IGLV(I)IGLV(I)-63 IGLV(I)-63*01 (45) P 22q11.2 V1-24P D87022 [9] MAP 13540-13836 * BK075720✤ [12] 70367-70867
BK075721✤ [12] 70369-70869
IMGT000280 [13] ° 70520-70816 *
IMGT000293 [3,8] 70365-70865
IMGT000319 [7] 70367-70867
IMGT000329 [7] 70326-70826
IGLV(I)IGLV(I)-63 IGLV(I)-63*02 P (12) 22q11.2 IMGT000225 [5,10] ° MAP 63695-64195 IMGT000318 [11] 70389-70889
IGLV(I)IGLV(I)-68 IGLV(I)-68*01 (45) P 22q11.2 V1-26P D86993 [9] MAP 18459-18751 * BK075720✤ [12] 23499-23791 *
BK075721✤ [12] 23501-23793 *
IMGT000225 [5,10] ° 16838-17130 *
IMGT000280 [13] ° 23499-23791 *
IMGT000293 [3,8] 23497-23789 *
IMGT000319 [7] 23501-23793 *
IMGT000329 [7] 23495-23787 *
IGLV(I)IGLV(I)-70 IGLV(I)-70*01 (45) P 22q11.2 V1-27P D86993 [9] MAP 11807-12099 * BK075720✤ [12] 16847-17139 *
BK075721✤ [12] 16847-17139 *
IMGT000225 [5,10] ° 10001-10517
IMGT000280 [13] ° 16662-17178
IMGT000293 [3,8] 16847-17139 *
IMGT000319 [7] 16664-17180
IGLV(I)IGLV(I)-70 IGLV(I)-70*02 P (13) 22q11.2 IMGT000329 [7] MAP 16662-17178
IGLV(I)IGLV(I)-70-1 IGLV(I)-70-1*01 P (10) 22q11.2 IMGT000225 [5,10] ° MAP <3340-3516 * BK075720✤ [12] 10001-10177 *
BK075721✤ [12] 10001-10177 *
IMGT000280 [13] ° 10001-10177 *
IMGT000293 [3,8] 10001-10177 *
IMGT000319 [7] 10001-10177 *
IMGT000329 [7] 10001-10177 *
IGLV(II)IGLV(II)-9-1 IGLV(II)-9-1*01 P (14) 22q11.2 IMGT000225 [5,10] ° MAP 798595-798892 * BK075720✤ [12] 811182-811479 *
BK075721✤ [12] 811093-811390 *
IMGT000280 [13] ° 814581-814878 *
IMGT000293 [3,8] 811205-811502 *
IMGT000318 [11] 805347-805644 *
IMGT000319 [7] 820585-820882 *
IMGT000329 [7] 826179-826476 *
IGLV(II)IGLV(II)-15-1 IGLV(II)-15-1*01 P (15) 22q11.2 IMGT000225 [5,10] ° MAP <734302-734599 * IMGT000318 [11] 741196-741493 *
IMGT000329 [7] 761977-762274 *
IGLV(II)IGLV(II)-15-1 IGLV(II)-15-1*02 P (16) 22q11.2 IMGT000280 [13] ° MAP 750355-750719 BK075720✤ [12] 746985-747301 *
BK075721✤ [12] 746927-747243 *
IMGT000293 [3,8] 746998-747362
IMGT000319 [7] 756358-756722
IGLV(II)IGLV(II)-24-1 IGLV(II)-24-1*01 (45) P (17) 22q11.2 102D1 D86994 [9] MAP 27202-27485 * AC279213 [15] 19069-19352 *
ABC11_000047999300_E7 AC279318 [15] 34786-35069 *
BK075720✤ [12] 686355-686638 *
BK075721✤ [12] 686276-686559 *
IMGT000225 [5,10] ° 673652-673935 *
IMGT000280 [13] ° 689730-690013 *
IMGT000293 [3,8] 686367-686650 *
IMGT000318 [11] 680591-680874 *
IMGT000319 [7] 695729-696012 *
IMGT000329 [7] 701359-701642 *
IGLV(II)IGLV(II)-24-1 IGLV(II)-24-1*02 P (18) 22q11.2 IMGT000312 [3,8] MAP 680438-680721 *
IGLV(III)IGLV(III)-59-1 IGLV(III)-59-1*01 P (19) 22q11.2 30E12 D87000 [9] MAP 18801-19325 AC279212 [15] 20050-20339 *
BK075720✤ [12] 158806-159330
BK075721✤ [12] 158810-159334
IMGT000225 [5,10] ° 152276-152565 *
IMGT000293 [3,8] 164836-165360
IMGT000318 [11] 158840-159364
IMGT000329 [7] 164868-165392
IGLV(III)IGLV(III)-59-1 IGLV(III)-59-1*02 P (20) 22q11.2 ABC13_11_000047487500_B16 AC279317 [15] MAP 13283-13572 * IMGT000280 [13] ° 158783-159307
IMGT000319 [7] 164904-165428
IGLV(III)IGLV(III)-60-1 IGLV(III)-60-1*01 P (21) 22q11.2 IMGT000225 [5,10] ° MAP 141177-141626 AC279212 [15] 9099-9366 *
BK075720✤ [12] 147842-148291
BK075721✤ [12] 147846-148295
30E12 D87000 [9] 7980-8247 *
IMGT000280 [13] ° 147964-148231 *
IMGT000319 [7] 153941-154390
IMGT000329 [7] 153904-154353
IGLV(III)IGLV(III)-60-1 IGLV(III)-60-1*02 P (22) 22q11.2 ABC13_11_000047487500_B16 AC279317 [15] MAP 2331-2599 * IMGT000293 [3,8] 154027-154295 *
IGLV(III)IGLV(III)-60-2 IGLV(III)-60-2*01 P (10) 22q11.2 IMGT000225 [5,10] ° MAP <95952-96099 * BK075720✤ [12] 102626-102773 *
BK075721✤ [12] 102625-102772 *
IMGT000280 [13] ° 102606-102753 *
IMGT000293 [3,8] 102631-102778 *
IMGT000318 [11] 102655-102802 *
IMGT000319 [7] 102624-102771 *
IMGT000329 [7] 102585-102732 *
IGLV(IV)IGLV(IV)-53 IGLV(IV)-53*01 (45) P 22q11.2 V4-5P D86996 [9] MAP 33365-33677 * BK075720✤ [12] 210405-210717 *
BK075721✤ [12] 210408-210720 *
IMGT000225 [5,10] ° 203572-204097
IMGT000319 [7] 216508-216820 *
IMGT000329 [7] 216475-216787 *
IGLV(IV)IGLV(IV)-53 IGLV(IV)-53*02 (45) P (23) 22q11.2 AC279220 [15] MAP 24230-24542 * IMGT000280 [13] ° 210236-210761
IMGT000293 [3,8] 216451-216763 *
IMGT000318 [11] 210674-210986 *
IGLV(IV)IGLV(IV)-53 IGLV(IV)-53*03 P (24) 22q11.2 ABC11_2_1_000049654800_O19 OL352713 [14] 40333-40646 *
IGLV(IV)IGLV(IV)-55-1 IGLV(IV)-55-1*01 (45) P (25) 22q11.2 23F1 D86996 [9] MAP 12576-12876 * AC279220 [15] 3438-3738 *
BK075720✤ [12] 189620-189920 *
BK075721✤ [12] 189624-189924 *
IMGT000293 [3,8] 195640-195940 *
IMGT000319 [7] 195718-196018 *
IMGT000329 [7] 195682-195982 *
IGLV(IV)IGLV(IV)-55-1 IGLV(IV)-55-1*02 P (26) 22q11.2 IMGT000225 [5,10] ° MAP 182949-183249 * IMGT000280 [13] ° 189593-189893 *
IMGT000318 [11] 189848-190148 *
IGLV(IV)IGLV(IV)-59 IGLV(IV)-59*01 (45) P 22q11.2 V4-7P D87000 [9] MAP 29557-30101 AC279212 [15] 30880-31178 *
ABC13_11_000047487500_B16 AC279317 [15] 24105-24403 *
BK075720✤ [12] 169561-170105
BK075721✤ [12] 169565-170109
IMGT000293 [3,8] 175588-176132
IMGT000318 [11] 169592-170136
IMGT000319 [7] 175659-176203
IMGT000329 [7] 175623-176167
IGLV(IV)IGLV(IV)-59 IGLV(IV)-59*02 P (27) 22q11.2 IMGT000225 [5,10] ° MAP 162900-163444 IMGT000280 [13] ° 169541-170085
IGLV(IV)IGLV(IV)-59 IGLV(IV)-59*03 P (27) 22q11.2 IMGT000312 [3,8] MAP 168813-169357
IGLV(IV)IGLV(IV)-61-1 IGLV(IV)-61-1*01 P (28) 22q11.2 IMGT000225 [5,10] ° MAP <71848-72047 * BK075720✤ [12] 78522-78721 *
BK075721✤ [12] 78523-78722 *
IMGT000280 [13] ° 78502-78701 *
IMGT000293 [3,8] 78520-78719 *
IMGT000318 [11] 78543-78742 *
IMGT000319 [7] 78523-78722 *
IMGT000329 [7] 78482-78681 *
IGLV(IV)IGLV(IV)-64 IGLV(IV)-64*01 (45) P 22q11.2 V4-8P D87022 [9] MAP 8968-9286 * BK075721✤ [12] 65786-66309
IGLV(IV)IGLV(IV)-64 IGLV(IV)-64*02 P (12) 22q11.2 IMGT000225 [5,10] ° MAP 59111-59634 BK075720✤ [12] 65784-66307
IMGT000280 [13] ° 65768-66291
IMGT000293 [3,8] 65782-66305
IMGT000318 [11] 65804-66327
IMGT000319 [7] 65784-66307
IMGT000329 [7] 65743-66266
IGLV(IV)IGLV(IV)-65 IGLV(IV)-65*01 (45) P 22q11.2 V4-9P D87022 [9] 4009-4315 *
IGLV(IV)IGLV(IV)-65 IGLV(IV)-65*02 P (29) 22q11.2 IMGT000225 [5,10] ° 54150-54671
IGLV(IV)IGLV(IV)-65 IGLV(IV)-65*03 P (12) 22q11.2 IMGT000280 [13] ° MAP 60807-61328 BK075720✤ [12] 60823-61344
BK075721✤ [12] 60825-61346
IMGT000293 [3,8] 60821-61342
IMGT000318 [11] 60843-61364
IMGT000319 [7] 60823-61344
IMGT000329 [7] 60782-61303
IGLV(IV)IGLV(IV)-66-1 (47) IGLV(IV)-66-1*01 (45) P (30) 22q11.2 D87004 [9] MAP 5100-5415 * BK075720✤ [12] 48924-49444
BK075721✤ [12] 48926-49446
IMGT000225 [5,10] ° 42415-42730 *
IMGT000293 [3,8] 48922-49442
IMGT000318 [11] 48928-49448
IMGT000319 [7] 49092-49407 *
IMGT000329 [7] 49050-49365 *
IGLV(IV)IGLV(IV)-66-1 IGLV(IV)-66-1*02 P (31) 22q11.2 IMGT000280 [13] ° MAP 48913-49433
IGLV(V)IGLV(V)-58 IGLV(V)-58*01 (45) P (12) 22q11.2 IMGT000225 [5,10] ° MAP 166321-166858 AC279212 [15] 34596-34903 *
BK075720✤ [12] 172982-173519
BK075721✤ [12] 172986-173523
V5-3P D87000 [9] 33165-33472 *
IMGT000280 [13] ° 173149-173456 *
IMGT000293 [3,8] 179009-179546
IMGT000319 [7] 179080-179617
IMGT000329 [7] 179044-179581
IGLV(V)IGLV(V)-58 IGLV(V)-58*02 (45) P (12) 22q11.2 ABC13_11_000047487500_B16 AC279317 [15] 27464-27771 *
IGLV(V)IGLV(V)-58 IGLV(V)-58*03 P (12) 22q11.2 ABC11_2_1_000049654800_O19 OL352713 [14] 3180-3486 *
IGLV(V)IGLV(V)-61-1 IGLV(V)-61-1*01 P (32) 22q11.2 IMGT000225 [5,10] ° MAP 81840->82039 * BK075720✤ [12] 88514-88713 *
BK075721✤ [12] 88513-88712 *
IMGT000280 [13] ° 88494-88693 *
IMGT000293 [3,8] 88507-88706 *
IMGT000318 [11] 88530-88729 *
IMGT000319 [7] 88513-88712 *
IMGT000329 [7] 88473-88672 *
IGLV(V)IGLV(V)-66 IGLV(V)-66*01 (45) P (33) 22q11.2 V5-5P D87004 [9] MAP 7867-8167 * BK075720✤ [12] 51677-52202
BK075721✤ [12] 51679-52204
IMGT000293 [3,8] 51675-52200
IMGT000329 [7] 51637-52162
IGLV(V)IGLV(V)-66 IGLV(V)-66*02 P (34) 22q11.2 IMGT000225 [5,10] ° MAP 45002-45527 IMGT000280 [13] ° 51666-52185
IMGT000318 [11] 51682-52207
IGLV(V)IGLV(V)-66 IGLV(V)-66*03 P (34) 22q11.2 IMGT000319 [7] MAP 51859-52159 *
IGLV(VI)IGLV(VI)-16-1 IGLV(VI)-16-1*01 P (35) 22q11.2 IMGT000225 [5,10] ° MAP 727816-728456 BK075720✤ [12] 740519-741159
IMGT000293 [3,8] 740536-741176
IMGT000318 [11] 734739-735379
IMGT000319 [7] 749896-750536
IMGT000329 [7] 755515-756155
IGLV(VI)IGLV(VI)-16-1 IGLV(VI)-16-1*02 P (36) 22q11.2 IMGT000280 [13] ° MAP 743888-744658 BK075721✤ [12] 740446-741216
IGLV(VI)IGLV(VI)-22-1 (48) IGLV(VI)-22-1*01 (43) P 22q11.2 lambdavg2 X71351 [6] 214-502 *
IGLV(VI)IGLV(VI)-22-1 (48) IGLV(VI)-22-1*02 (43) P (37) 22q11.2 AC279208 [15] MAP 5545-5833 * AC279213 [15] 30096-30384 *
AC279219 [15] 5545-5833 *
BK075721✤ [12] 697303-697591 *
IMGT000225 [5,10] ° 684678-684966 *
IMGT000293 [3,8] 697394-697682 *
IMGT000318 [11] 691618-691906 *
IMGT000319 [7] 706756-707044 *
IMGT000329 [7] 712386-712674 *
IGLV(VI)IGLV(VI)-22-1 (48) IGLV(VI)-22-1*03 (43) P (37) 22q11.2 AC279210 [15] MAP 2193-2485 * BK075720✤ [12] 697382-697674 *
IMGT000280 [13] ° 700757-701049 *
IGLV(VI)IGLV(VI)-25-1 (48) IGLV(VI)-25-1*01 (43) P (46) 22q11.2 lambdavg3 D86994 [9] MAP 16572-16861 * AC279213 [15] 8480-8769 *
ABC11_000047999300_E7 AC279318 [15] 24025-24027 *
BK075720✤ [12] 675787-676076 *
IMGT000225 [5,10] ° 663033-663322 *
IMGT000280 [13] ° 679162-679451 *
IMGT000293 [3,8] 675780-676069 *
IMGT000319 [7] 685099-685388 *
IMGT000329 [7] 690765-691054 *
IGLV(VI)IGLV(VI)-25-1 IGLV(VI)-25-1*02 P (38) 22q11.2 BK075721✤ [12] MAP 675658-675947 * IMGT000318 [11] 670002-670291 *
IGLV(VII)IGLV(VII)-41-1 (49) IGLV(VII)-41-1*01 (44) P 22q11.2 lambdavg1 X99568 [1] 1-335 *
IGLV(VII)IGLV(VII)-41-1 IGLV(VII)-41-1*02 P (39) 22q11.2 IMGT000225 [5,10] ° MAP <382209-382507 * BK075720✤ [12] 394828-395126 *
BK075721✤ [12] 394824-395122 *
IMGT000280 [13] ° 398129-398427 *
IMGT000293 [3,8] 394837-395135 *
IMGT000318 [11] 389051-389349 *
IMGT000319 [7] 404246-404544 *
IMGT000329 [7] 409996-410294 *
IGLV(VII)IGLV(VII)-59-1 IGLV(VII)-59-1*01 P (40) 22q11.2 IMGT000225 [5,10] ° MAP <150037->150235 * BK075720✤ [12] 156702-156900 *
BK075721✤ [12] 156706-156904 *
IMGT000280 [13] ° 156679-156877 *
IMGT000318 [11] 156739-156937 *
IGLV(VII)IGLV(VII)-59-1 IGLV(VII)-59-1*02 P (41) 22q11.2 IMGT000293 [3,8] MAP <162735->162933 * IMGT000319 [7] 162800-162998 *
IMGT000329 [7] 162764-162962 *
IGLV(VII)IGLV(VII)-68-1 IGLV(VII)-68-1*01 P (42) 22q11.2 IMGT000225 [5,10] ° MAP 16395->16685 * BK075720✤ [12] 23056-23346 *
BK075721✤ [12] 23058-23348 *
IMGT000280 [13] ° 23056-23346 *
IMGT000293 [3,8] 23054-23344 *
IMGT000319 [7] 23058-23348 *
IMGT000329 [7] 23052-23342 *

✤ : NCBI accession number that correspond to a previously internal IMGT accession number. See the correspondence table.

IMGT notes: ↑
  1. truncated pseudogene not assigned to subgroups with functional genes
  2. No L-PART1, frameshift in V-REGION: several insertions and deletions
  3. STOP-CODON in L-PART1
  4. no L-PART1, frameshift in FR1-IMGT: insertion of 16 nt
  5. no L-PART1, no L-PART2
  6. STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions
  7. frameshift in L-PART1 causing defectuous DONOR-SPLICE, frameshifts in V-REGION: several insertions and deletions
  8. no L-PART1, frameshifts in V-REGION: several insertions and deletions
  9. no L-PART1, frameshift in V-REGION: insertion of 16 nt in FR1-IMGT
  10. no L-PART1, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes
  11. frameshift in V-REGION: several insertions and deletions
  12. frameshifts in V-REGION: several insertions and deletions
  13. STOP-CODON in V-REGION: position 95
  14. no L-PART1, frameshift in V-REGION: deletion of 1 nt in CDR1-IMGT
  15. no L-PART1, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, frameshift in V-REGION: deletion of 1 nt in CDR1-IMGT
  16. no L-PART1, no L-PART2, frameshifts in V-REGION: several insertions and deletions
  17. No L-PART1, frameshift in L-PART2, frameshift in V-REGION: several insertions and deletions, No V-RS
  18. no L-PART1+frameshift in L-PART2+too many frameshifts+no V-RS
  19. STOP-CODON in FR1-IMGT, frameshift in V-REGION: several insertions and deletions in FR3-IMGT, no V-NONAMER
  20. STOP-CODON in FR1-IMGT: position 1 and 15, frameshift in V-REGION: several insertions and deletions in FR3-IMGT
  21. no INIT-CODON: Ile instead of Met, no ACCEPTOR-SPLICE, frameshifts in V-REGION: several insertions and deletions
  22. No L-PART1, deletion of 24 nt in V-REGION, frameshift in V-REGION: several insertions and deletions
  23. frameshift in V-REGION: several insertions and deletions, no V-NONAMER
  24. frameshift in L-PART1: deletion of 1 nt causing defectuous DONOR-SPLICE, frameshifts in V-REGION: several insertions and deletions
  25. No L-PART1, frameshift in V-REGION: several insertions and deletions, no V-NONAMER
  26. No L-PART1, No L-PART2, frameshift in V-REGION: several insertions and deletions, no V-NONAMER
  27. no INIT-CODON: Leu instead of Met, STOP-CODON in L-PART1, frameshift in V-REGION: insertion of 8 nt in FR1-IMGT
  28. no L-PART1, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, no V-NONAMER
  29. several STOP-CODON in V-REGION, frameshifts in V-REGION: several insertions and deletions
  30. L-PART1 not found, frameshifts in FR3-IMGT
  31. no INIT-CODON: Val instead of Met, frameshift in L-PART1:deletion of 1 nt causing defectuous DONOR-SPLICE, frameshift in V-REGION: insertion of 2 nt in FR3-IMGT
  32. no L-PART1, truncated pseudogene not assigned to subgroups with functional genes, no V-RS
  33. frameshifts in V-REGION, L-PART1 not found
  34. no DONOR-SPLICE, frameshift in V-REGION: deletion of 2 nt in FR1-IMGT
  35. frameshift in L-PART1 causing defectuous DONOR-SPLICE, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes
  36. frameshift in L-PART1 causing defectuous DONOR-SPLICE, no L-PART2, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes
  37. Frameshift in L-PART1, frameshift in V-REGION: several insertions and deletions, no V-RS
  38. STOP-CODON in L-PART1, truncated pseudogene not assigned to subgroups with functional genes
  39. no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, no V-NONAMER
  40. no L-PART1, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, truncated pseudogene not assigned to subgroups with functional genes, no V-RS
  41. no L-PART1, no L-PART2, no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, truncated pseudogene not assigned to subgroups with functional genes, no V-RS,
  42. frameshift in L-PART2, no L-PART1, truncated pseudogene not assigned to subgroups with functional genes, no V-RS
  43. V-CLUSTER: A.
  44. V-CLUSTER: B.
  45. V-CLUSTER: C.
  46. frameshift in L-PART1, frameshift in L-PART2, frameshift in V-REGION: several insertions and deletions, no V-RS.
  47. IGLV(IV)-66-1 has been identified in D87004 by IMGT curators (Folch, G., Giudicelli, V. and Lefranc, M.-P., IMGT On-line, 14/12/1999).
  48. An additional vestigial pseudogene lambdavg3, which has 92% identity with lambdavg2 has been identified in D86994 by IMGT curators (N. Bosc, M.-P. Lefranc), between IGLV3-25 and IGLV3-26 (5.7kb downstream from IGLV3-26). The lambdavg2 and lambdavg3 sequences define a new clan IGLV(VI) and are designated as IGLV(VI)-22-1 (X71351)[18] and IGLV(VI)-25-1 (D86994)[26], respectively.
  49. The highly diverged vestigial pseudogene lambdavgl (X99568)[5] has no CONSERVED_TRP and no 2nd_CYS (confirmed with D86999[26] although this accession number contains many sequencing or typing errors). Since this lambdavg1 sequence is unique in the human genome and can therefore be used as a STS (Sequence Tagged Site)[5] , the lambdavg1 was attributed to a new clan IGLV(VII) and designated as IGLV(VII)-41-1.
IMGT references: ↑
  1. Alexandre D. et al., First genomic sequence of a human Ig variable lambda gene belonging to subgroup I. Functional genes, pseudogenes and vestigial sequences are interspersed in the IGLV locus, Nucleic Acids Res, vol. 17, no. 10, 1989, pp. 3975-3975. DOI: 10.1093/nar/17.10.3975
  2. Chuchana P. et al., The IGLVA gene as a STS in the human immunoglobulin lambda light chain variable gene locus (located at 22q11), Nucleic Acids Res, vol. 19, no. 17, 1991, pp. 4786-4786. DOI: 10.1093/nar/19.17.4786
  3. Chu et al., Approaching an Error-Free Diploid Human Genome Assembly of East Asian Origin, (misc) bioRxivorg, 2025, DOI: 10.1101/2025.08.01.667781
  4. Chu et al., Direct Submission, Computational Biology, Beijing Institute of Genomics, Chinese Academy of Sciences / China National Center for Bioinformation. Submitted (16-AUG-2025). NGDC, Beijing, 100101, China.
  5. Cole,C.G. et al., Finishing the finished human chromosome 22 sequence, Genome Biol, vol. 9, no. 5, 2008, pp. R78-.
  6. Frippiat J.P. and Lefranc M.P, Genomic organisation of 34 kb of the human immunoglobulin lambda locus (IGLV): restriction map and sequences of new V lambda III genes, Mol. Immunol, vol. 31, no. 9, 1994, pp. 657-670. DOI: 10.1016/0161-5890(94)90175-9
  7. Giunta S. et al., Diploid T2T reference genome of the H9 human embryonic stem cell, Unpublished.
  8. He et al., T2T YAO: A Telomere to telomere Assembled Diploid Reference Genome for Han Chinese, Genomics Proteomics & Bioinformatics 21(6): 1085–1100 (2023), DOI: 10.1016/j.gpb.2023.08.001
  9. Kawasaki K. et al., One-megabase sequence analysis of the human immunoglobulin lambda gene locus, Genome Res, vol. 7, no. 3, 1997, pp. 250-261. PUBMED: 9074928
  10. Lander,E.S. et al., Initial sequencing and analysis of the human genome, International Human Genome Sequencing Consortium Nature, vol. 409, no. 6822, 2001, pp. 860-921.
  11. Liao W.W. et al., A draft human pangenome reference, Nature, vol. 617, no. 7960, 2023, pp. 312-324. PUBMED: 37165242
  12. Manso T. et al., IMGT(R) databases, related tools and web resources through three main axes of research and development, Nucleic Acids Res, vol. 50, no. D1, 2022, pp. 1262-1272.
  13. Nurk S. et al., The complete sequence of a human genome, Science, vol. 376, no. 6588, 2022, pp. 44-53. PUBMED: 35357919
  14. Rodriguez,O.L. et al., An ethnically diverse genomic reference resource for human immune receptor gene loci, Unpublished.
  15. Rodriguez O.L. et al., An ethnically diverse genomic reference resource for human immune receptor gene loci, Unpublished.