TRGV1 subgroup

TRGV9
TRGV11

Human TRGV1

Click here to see Part 1 - EcoRI and TaqI alleles and frequencies
Part 2 - EcoRI and TaqI haplotypes and frequencies

Part 3 - Combined EcoRI/TaqI haplotypes and frequencies

References for this table: Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989)
Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991)

Probe: pV3S clone (TRGVgammaI probe) [1]

TRGV1 haplotypes Enzymes Number of TRGV1 genes Polymorphism (1) Frequencies
EcoRI TaqI French
[2] 		Lebanese
[2] 		Tunisian
[2] 		Black African
[2] 		Chinese
[3]
TRGV1*1 *R1 *T1 9 RS 0.69 0.59 0.59 0.50 0.72
TRGV1*2 *R2 *T2 9 RS 0.10 0.19 0.16 0.17 0.09
TRGV1*3 *R3 *T3 7 D 0.21 0.20 0.16 0.13 0.15
TRGV1*4 *R4 *T4 10 I 0.00 0.00 0.04 0.13 0.00
TRGV1*5 *R2 *T5 9 RS 0.00 0.00 0.02 0.07 0.00
TRGV1*6 *R1 *T6 9 RS 0.00 0.02 0.02 0.00 0.00
TRGV1*7 *R2 *T6 9 RS 0.00 0.00 0.01 0.00 0.00
TRGV1*8 *R5 *T1 9 RS 0.00 0.00 0.00 0.00 0.01
TRGV1*9 *R1 *T7 9 RS 0.00 0.00 0.00 0.00 0.01
TRGV1*10 *R3 *T8 7 D, RS 0.00 0.00 0.00 0.00 0.02

IMGT notes:

(1) RS, polymorphic Restriction Sites; D, Deletion; I, Insertion.

References:

[1] Lefranc, M.-P. et al., Cell, 45, 237-246 (1986).
[2] Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989).
[3] Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991).

Created: 12/05/1999
Authors: Violaine Moreau and Marie-Paule Lefranc