TRGV1 subgroup

TRGV9
TRGV11

Human TRGV1 subgroup

Click here to see Part 2 - EcoRI and TaqI haplotypes and frequencies
Part 3 - Combined EcoRI/TaqI haplotypes and frequencies

Part 1 - EcoRI and TaqI alleles and frequencies

References for this table: Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989)
Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991)

Probe : pV3S clone (TRGVgammaI probe) [1]

TRGV gene name (1) RFLP alleles Enzymes Fragments (kb) (2) Polymorphism type (3) Frequencies NCBI genome
Constant Polymorphic French [2] Lebanese [2] Tunisian [2] Black African [2] Chinese [3]
TRGV1 *B1 TaqI 8.5 0.8+1.0       16 RS 0.69 0.59 0.59 0.50 0.74 6973 [2][3]
*B2 22 RS 0.10 0.19 0.16 0.17 0.09
*B3 17 RS 0.21 0.20 0.20 0.26 0.17
*B4 15 RS 0.00 0.00 0.01 0.07 0.00
*B5 12.8 RS 0.00 0.02 0.03 0.00 0.00
TRGV2 *A1 EcoRI 5.8 3.7 9.3 3.6 3.8 1.8+7.0 RS 0.90 0.81 0.81 0.76 0.90 6974 [2][3]
*A2 1.8+9.4 RS 0.10 0.19 0.19 0.24 0.09
*A3 1.6+7.0 RS 0.00 0.00 0.00 0.00 0.01
TRGV4 *A1 EcoRI 5.8 3.7 9.3 3.6 3.8 2.4+3.1 RS 0.69 0.61 0.61 0.50 0.74 6977 [2][3]
*A2 9.4+3.1 RS 0.10 0.19 0.19 0.24 0.09
*A3 - D 0.21 0.20 0.16 0.13 0.17
*A4 6.4+3.1 I 0.00 0.00 0.04 0.13 0.00
*B1 TaqI 8.5 0.8+1.0       6 RS 0.69 0.59 0.59 0.50 0.74
*B2 22 RS 0.10 0.19 0.16 0.17 0.09
*B3 - D 0.21 0.20 0.16 0.13 0.17
*B4 11 I 0.00 0.00 0.04 0.13 0.00
*B5 7 RS 0.00 0.00 0.01 0.07 0.00
*B6 4.2 RS 0.00 0.02 0.03 0.00 0.00
TRGV5 *A1 EcoRI 5.8 3.7 9.3 3.6 3.8 3.7   0.79 0.80 0.84 0.87 0.83 6978 [2][3]
*A2 - D 0.21 0.20 0.16 0.13 0.17
*B1 TaqI 8.5 0.8+1.0       4.2 RS 0.79 0.80 0.84 0.87 0.82
*B2 4 RS 0.00 0.00 0.00 0.00 0.01
*B3 - D 0.21 0.20 0.16 0.13 0.17
TRGV7 *B1 TaqI 8.5 0.8+1.0       3.7 RS 1.00 1.00 1.00 1.00 0.98 6981 [2][3]
*B2 3 RS 0.00 0.00 0.00 0.00 0.02

IMGT notes:

(1) In this table are only shown the genes from the TRGV1 subgroup for which RFLP alleles have been described.
(2) Fragments detected with the pV3S clone (TRGVgammaI probe) [1].
(3) RS, polymorphic Restriction Sites; D, Deletion; I, Insertion.

References:

[1] Lefranc, M.-P. et al., Cell, 45, 237-246 (1986).
[2] Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989).
[3] Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991).

Created: 12/05/1999
Authors: Violaine Moreau and Marie-Paule Lefranc