Print of this table: Scaviner, D. et al., Exp. Clin. Immunogenet., 16, 234-240 (1999). PMID:10575277 UPDATE: 22/10/2002

Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.

Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown. Two pseudogenes are included: IGHV3-19 which has no L-PART2, and IGHV3-47 which has no INIT-CODON.

Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).


         FR1-IMGT            CDR1-IMGT        FR2-IMGT      CDR2-IMGT                   FR3-IMGT                CDR3-IMGT
          (1-26)              (27-38)         (39-55)        (56-65)                    (66-104)                (105-117)
AccNumAllele
       A             B           BC         C        C'        C'C"       C"         D           E          F       FG
    (1-15)        (16-26)     (27-38)    (39-46)   (47-55)   (56-65)    (66-74)   (75-84)     (85-96)    (97-104)     
——————————————> ——————————>              ———————> ————————>            ————————> —————————> ———————————> ———————>     
1        10  15 16    23 26 27        38 3941  46 47     55 56      65 66     74 75   80 84 85  89    96 97   104 105     
|........|....| |......|..| |..........| |.|....| |.......| |........| |.......| |....|...| |...|......| |......| |...
Z18904,IGHV1-c, 
............XKS GASVKVSCSFS GFTI....TSYG IHWVQQSP GQGLEWMGW INPG..NGSP SYAKKFQ.G RFTMTRDMST TTAYTDLSSLTS EDMAVYYY AR
Z12305,IGHV1-f, 
EVQLVQSGA.EVKKP GATVKISCKVS GYTF....TDYY MHWVQQAP GKGLEWMGL VDPE..DGET IYAEKFQ.G RVTITADTST DTAYMELSSLRS EDTAVYYC AT
X07448,IGHV1-2, 
QVQLVQSGA.EVKKP GASVKVSCKAS GYTF....TGYY MHWVRQAP GQGLEWMGR INPN..SGGT NYAQKFQ.G RVTSTRDTSI STAYMELSRLRS DDTVVYYC AR
X62109,IGHV1-3, 
QVQLVQSGA.EVKKP GASVKVSCKAS GYTF....TSYA MHWVRQAP GQRLEWMGW INAG..NGNT KYSQKFQ.G RVTITRDTSA STAYMELSSLRS EDTAVYYC AR
M99637,IGHV1-8, 
QVQLVQSGA.EVKKP GASVKVSCKAS GYTF....TSYD INWVRQAT GQGLEWMGW MNPN..SGNT GYAQKFQ.G RVTMTRNTSI STAYMELSSLRS EDTAVYYC AR
M99641,IGHV1-18, 
QVQLVQSGA.EVKKP GASVKVSCKAS GYTF....TSYG ISWVRQAP GQGLEWMGW ISAY..NGNT NYAQKLQ.G RVTMTTDTST STAYMELRSLRS DDTAVYYC AR
M99642,IGHV1-24, 
QVQLVQSGA.EVKKP GASVKVSCKVS GYTL....TELS MHWVRQAP GKGLEWMGG FDPE..DGET IYAQKFQ.G RVTMTEDTST DTAYMELSSLRS EDTAVYYC AT
X92209,IGHV1-45, 
QMQLVQSGA.EVKKT GSSVKVSCKAS GYTF....TYRY LHWVRQAP GQALEWMGW ITPF..NGNT NYAQKFQ.D RVTITRDRSM STAYMELSSLRS EDTAMYYC AR
X92343,IGHV1-46, 
QVQLVQSGA.EVKKP GASVKVSCKAS GYTF....TSYY MHWVRQAP GQGLEWMGI INPS..GGST SYAQKFQ.G RVTMTRDTST STVYMELSSLRS EDTAVYYC AR
M29809,IGHV1-58, 
QMQLVQSGP.EVKKP GTSVKVSCKAS GFTF....TSSA VQWVRQAR GQRLEWIGW IVVG..SGNT NYAQKFQ.E RVTITRDMST STAYMELSSLRS EDTAVYYC AA
AB019437,IGHV1-68, 
QVQLGQSEA.EVKKP GASVKVSCKAS GYTF....TCCS LHWLQQAP GQGLERMRW ITLY..NGNT NYAKKFQ.G RVTITRDMSL RTAYIELSSLRS EDSAVYYW AR
L22582,IGHV1-69, 
QVQLVQSGA.EVKKP GSSVKVSCKAS GGTF....SSYA ISWVRQAP GQGLEWMGG IIPI..FGTA NYAQKFQ.G RVTITADEST STAYMELSSLRS EDTAVYYC AR
X62111,IGHV2-5, 
QITLKESGP.TLVKP TQTLTLTCTFS GFSLS..TSGVG VGWIRQPP GKALEWLAL IYWN...DDK RYSPSLK.S RLTITKDTSK NQVVLTMTNMDP VDTATYYC AHR
M99647,IGHV2-10, 
QVTLKESGP.ALVKP TQTLMLTCTFS GFSLS..TSGMG VG*ICQPS AKALEWLAH IY*N...DNK YYSPSLK.S RLIISKDTSK NEVVLTVINMDI VDTATHYC ARR
M99648,IGHV2-26, 
QVTLKESGP.VLVKP TETLTLTCTVS GFSLS..NARMG VSWIRQPP GKALEWLAH IFSN...DEK SYSTSLK.S RLTISKDTSK SQVVLTMTNMDP VDTATYYC ARI
L21969,IGHV2-70, 
QVTLRESGP.ALVKP TQTLTLTCTFS GFSLS..TSGMC VSWIRQPP GKALEWLAL IDWD...DDK YYSTSLK.T RLTISKDTSK NQVVLTMTNMDP VDTATYYC ARI
Z18898,IGHV3-d, 
EVQLVESRG.VLVQP GGSLRLSCAAS GFTV....SSNE MSWVRQAP GKGLEWVSS ISG....GST YYADSRK.G RFTISRDNSK NTLHLQMNSLRA EDTAVYYC KK
AJ879484,IGHV3-h, (4)
EVQLVESGG.GLVKP GGSLRLSCAAS GFTF....SDYY MNWVRQAP GKGLEWVSS ISSS...STI YYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTAVYYC AR
HM855939,IGH3-NL1, 
QVQLVESGG.GVVQP GGSLRLSCAAS GFTF....SSYG MHWVRQAP GKGLEWVSV IYSG..GSST YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AK
M99649,IGHV3-7, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SSYW MSWVRQAP GKGLEWVAN IKQD..GSEK YYVDSVK.G RFTISRDNAK NSLYLQMNSLRA EDTAVYYC AR
M99651,IGHV3-9, 
EVQLVESGG.GLVQP GRSLRLSCAAS GFTF....DDYA MHWVRQAP GKGLEWVSG ISWN..SGSI GYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTALYYC AKD
M99652,IGHV3-11, 
QVQLVESGG.GLVKP GGSLRLSCAAS GFTF....SDYY MSWIRQAP GKGLEWVSY ISSS..GSTI YYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTAVYYC AR
X92217,IGHV3-13, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SSYD MHWVRQAT GKGLEWVSA IGTA...GDT YYPGSVK.G RFTISRENAK NSLYLQMNSLRA GDTAVYYC AR
X92216,IGHV3-15, 
EVQLVESGG.GLVKP GGSLRLSCAAS GFTF....SNAW MSWVRQAP GKGLEWVGR IKSKTDGGTT DYAAPVK.G RFTISRDDSK NTLYLQMNSLKT EDTAVYYC TT
M99655,IGHV3-16, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SNSD MNWARKAP GKGLEWVSG VSWN..GSRT HYVDSVK.R RFIISRDNSR NSLYLQKNRRRA EDMAVYYC VR
M99656,IGHV3-19, (2)
TVQLVESGG.GLVEP GGSLRLSCAAS GFTF....SNSD MNWVRQAP GKGLEWVSG VSWN..GSRT HYADSVK.G RFIISRDNSR NFLYQQMNSLRP EDMAVYYC VR
M99657,IGHV3-20, 
EVQLVESGG.GVVRP GGSLRLSCAAS GFTF....DDYG MSWVRQAP GKGLEWVSG INWN..GGST GYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTALYHC AR
AB019439,IGHV3-21, 
EVQLVESGG.GLVKP GGSLRLSCAAS GFTF....SSYS MNWVRQAP GKGLEWVSS ISSS..SSYI YYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTAVYYC AR
M99659,IGHV3-22, 
EVHLVESGG.ALVQP GGSLRLSCAAS GFTF....SYYY MSGVRQAP GKGLEWVGF IRNKANGGTT E*TTSVK.G RFTISRDDSK SITYLQMKSLKT EDTAVYYC SR
M99660,IGHV3-23, 
EVQLLESGG.GLVQP GGSLRLSCAAS GFTF....SSYA MSWVRQAP GKGLEWVSA ISGS..GGST YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AK
M99661,IGHV3-25, 
EMQLVESGG.GLQKP AWSPRLSCAAS QFTF....SSYY MNCVRQAP GNGLELV*Q VNPN..GGST YLIDSGK.D RFNTSRDNAK NTLHLQMNSLKT EDTALY*C TR
M83134,IGHV3-30, 
QVQLVESGG.GVVQP GRSLRLSCAAS GFTF....SSYA MHWVRQAP GKGLEWVAV ISYD..GSNK YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AR
X92283,IGHV3-30-3, 
QVQLVESGG.GVVQP GRSLRLSCAAS GFTF....SSYA MHWVRQAP GKGLEWVAV ISYD..GSNK YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AR
AB019439,IGHV3-32, 
EVELIESIE.DLRQP GKFLRLSCVAS RFAF....SSF* MSRVHQSP GKGLE*VID IKDD..GSQI HHADSVK.G RFSISKDNAK NSLYLQMNTQRA EDVAVYGY T*G
AB019439,IGHV3-33, 
QVQLVESGG.GVVQP GRSLRLSCAAS GFTF....SSYG MHWVRQAP GKGLEWVAV IWYD..GSNK YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AR
M99666,IGHV3-35, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SNSD MNWVHQAP GKGLEWVSG VSWN..GSRT HYADSVK.G RFIISRDNSR NTLYLQTNSLRA EDTAVYYC VR
,M99669IGHV3-38, 
EVQLVESGG.GLVQP RGSLRLSCAAS GFTV....SSNE MSWIRQAP GKGLEWVSS ISG....GST YYADSRK.G RFTISRDNSK NTLYLQMNNLRA EGTAAYYC ARY
M99672,IGHV3-43, 
EVQLVESGG.VVVQP GGSLRLSCAAS GFTF....DDYT MHWVRQAP GKGLEWVSL ISWD..GGST YYADSVK.G RFTISRDNSK NSLYLQMNSLRT EDTALYYC AKD
Z18900,IGHV3-47, (1)
EDQLVESGG.GLVQP GGSLRPSCAAS GFAF....SSYA LHWVRRAP GKGLEWVSA IGTG...GDT YYADSVM.G RFTISRDNAK KSLYLHMNSLIA EDMAVYYC AR
M99675,IGHV3-48, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SSYS MNWVRQAP GKGLEWVSY ISSS..SSTI YYADSVK.G RFTISRDNAK NSLYLQMNSLRA EDTAVYYC AR
M99676,IGHV3-49, 
EVQLVESGG.GLVQP GRSLRLSCTAS GFTF....GDYA MSWFRQAP GKGLEWVGF IRSKAYGGTT EYTASVK.G RFTISRDGSK SIAYLQMNSLKT EDTAVYYC TR
M99678,IGHV3-52, 
EVQLVESG*.GLVQP GGSLRLSCAAS GFTF....SSSW MHWVCQAP EKGLEWVAD IKCD..GSEK YYVDSVK.G RLTISRDNAK NSLYLQVNSLRA EDMTVYYC VR
M99679,IGHV3-53, 
EVQLVESGG.GLIQP GGSLRLSCAAS GFTV....SSNY MSWVRQAP GKGLEWVSV IYSG...GST YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AR
M99680,IGHV3-54, 
EVQLVESEE.NQRQL GGSLRLSCADS GLTF....SSY* MSSDSQAP GKGLE*VVD I**D..RSQL CYAQSVK.S RFTISKENAK NSLCLQMNSLRA EGTAVYYC M*
AB019437,IGHV3-62, 
EVQLVESGE.GLVQP GGSLRLSCAAS GFTF....SSSA MHWVRQAP RKGL*WVSV ISTS..GDTV LYTDSVK.G RFTISRDNAQ NSLSLQMNSLRA EGTVVYYC VK
M99681,IGHV3-63, 
EVELIESIE.GLRQL GKFLRLSCVAS GFTF....SSY* MSWVNETL GKGLEGVID VKYD..GSQI YHADSVK.G RFTISKDNAK NSPYLQTNSLRA EDMTMHGC T*G
M99682,IGHV3-64, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SSYA MHWVRQAP GKGLEYVSA ISSN..GGST YYANSVK.G RFTISRDNSK NTLYLQMGSLRA EDMAVYYC AR
X92218,IGHV3-66, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTV....SSNY MSWVRQAP GKGLEWVSV IYSG...GST YYADSVK.G RFTISRDNSK NTLYLQMNSLRA EDTAVYYC AR
AB019437,IGHV3-71, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SDYY MSWVRQAP GKGLEWVGF IRNKANGGTT E*TTSVK.G RFTISRDDSK SITYLQMNSLRA EDTAVYYC AR
X92206,IGHV3-72, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SDHY MDWVRQAP GKGLEWVGR TRNKANSYTT EYAASVK.G RFTISRDDSK NSLYLQMNSLKT EDTAVYYC AR
X70197,IGHV3-73, 
EVQLVESGG.GLVQP GGSLKLSCAAS GFTF....SGSA MHWVRQAS GKGLEWVGR IRSKANSYAT AYAASVK.G RFTISRDDSK NTAYLQMNSLKT EDTAVYYC TR
L33851,IGHV3-74, 
EVQLVESGG.GLVQP GGSLRLSCAAS GFTF....SSYW MHWVRQAP GKGLVWVSR INSD..GSST SYADSVK.G RFTISRDNAK NTLYLQMNSLRA EDTAVYYC AR
Z12367,IGHV4-b, 
QVQLQESGP.GLVKP SETLSLTCAVS GYSIS...SGYY WGWIRQPP GKGLEWIGS IYHS...GST YYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
X05713,IGHV4-4, 
QVQLQESGP.GLVKP PGTLSLTCAVS GGSIS...SSNW WSWVRQPP GKGLEWIGE IYHS...GST NYNPSLK.S RVTISVDKSK NQFSLKLSSVTA ADTAVYCC AR
X05714,IGHV4-28, 
QVQLQESGP.GLVKP SDTLSLTCAVS GYSIS...SSNW WGWIRQPP GKGLEWIGY IYYS...GST YYNPSLK.S RVTMSVDTSK NQFSLKLSSVTA VDTAVYYC AR
L10089,IGHV4-30-2, 
QLQLQESGS.GLVKP SQTLSLTCAVS GGSIS..SGGYS WSWIRQPP GKGLEWIGY IYHS...GST YYNPSLK.S RVTISVDRSK NQFSLKLSSVTA ADTAVYYC AR
Z14238,IGHV4-30-4, 
QVQLQESGP.GLVKP SQTLSLTCTVS GGSIS..SGDYY WSWIRQPP GKGLEWIGY IYYS...GST YYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
L10098,IGHV4-31, 
QVQLQESGP.GLVKP SQTLSLTCTVS GGSIS..SGGYY WSWIRQHP GKGLEWIGY IYYS...GST YYNPSLK.S LVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
AB019439,IGHV4-34, 
QVQLQQWGA.GLLKP SETLSLTCAVY GGSF....SGYY WSWIRQPP GKGLEWIGE INHS...GST NYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
AB019439,IGHV4-39, 
QLQLQESGP.GLVKP SETLSLTCTVS GGSIS..SSSYY WGWIRQPP GKGLEWIGS IYYS...GST YYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
M99685,IGHV4-55, (3)
QVQLQESGP.GLVKP SETLSLICAVS GDSIS...SGNW *IWVRQPP GKGLEWIGE IHHS...GST YYNPSLK.S RITMSVDTSK NQFYLKLSSVTA ADTAVYYC AR
AB019438,IGHV4-59, 
QVQLQESGP.GLVKP SETLSLTCTVS GGSI....SSYY WSWIRQPP GKGLEWIGY IYYS...GST NYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
M29811,IGHV4-61, 
QVQLQESGP.GLVKP SETLSLTCTVS GGSVS..SGSYY WSWIRQPP GKGLEWIGY IYYS...GST NYNPSLK.S RVTISVDTSK NQFSLKLSSVTA ADTAVYYC AR
X92227,IGHV5-a, 
EVQLVQSGA.EVKKP GESLRISCKGS GYSF....TSYW ISWVRQMP GKGLEWMGR IDPS..DSYT NYSPSFQ.G HVTISADKSI STAYLQWSSLKA SDTAMYYC AR
M99686,IGHV5-51, 
EVQLVQSGA.EVKKP GESLKISCKGS GYSF....TSYW IGWVRQMP GKGLEWMGI IYPG..DSDT RYSPSFQ.G QVTISADKSI STAYLQWSSLKA SDTAMYYC AR
X92213,IGHV5-78, 
EVQLLQSAA.EVKRP GESLRISCKTS GYSF....TSYW IHWVRQMP GKELEWMGS IYPG..NSDT RYSPSFQ.G HVTISADSSS STAYLQWSSLKA SDAAMYYC VR
X92224,IGHV6-1, 
QVQLQQSGP.GLVKP SQTLSLTCAIS GDSVS..SNSAA WNWIRQSP SRGLEWLGR TYYRS.KWYN DYAVSVK.S RITINPDTSK NQFSLQLNSVTP EDTAVYYC AR
L10057,IGHV7-4-1, 
QVQLVQSGS.ELKKP GASVKVSCKAS GYTF....TSYA MNWVRQAP GQGLEWMGW INTN..TGNP TYAQGFT.G RFVFSLDTSV STAYLQICSLKA EDTAVYYC AR
AB019437,IGHV7-81, 
QVQLVQSGH.EVKQP GASVKVSCKAS GYSF....TTYG MNWVPQAP GQGLEWMGW FNTY..TGNP TYAQGFT.G RFVFSMDTSA STAYLQISSLKA EDMAMYYC AR
IMGT notes:
(1) Pseudogene, because no INIT-CODON, atg replaced by cac.
(2) Second part of the leader exon (L-PART2) is missing.
(3) Pseudogene, because of STOP-CODON at position 39, but the gene has been found rearranged. For that reason the IGHV4-55 gene has been added to IMGT/V-QUEST (May 2005).
(4) Pseudogene, because no INIT-CODON, atg replaced by aag.